Predictive models in Alzheimer's disease: an evaluation based on data mining techniques

Abstract

The increasing prevalence of Alzheimer's disease in older adults has raised significant concern in recent years. Aware of this challenge, this research set out to develop predictive models that allow early identification of people at risk for Alzheimer's disease, considering several variables associated with the disease. To achieve this objective, data mining techniques were employed, specifically the decision tree algorithm, using the RapidMiner Studio tool. The sample explore modify model and assess (SEMMA) methodology was implemented systematically at each stage of model development, ensuring an orderly and structured approach. The results obtained revealed that 45.00% of people with dementia present characteristics that identify them as candidates for confirmation of a diagnosis of Alzheimer's disease. In contrast, 52.78% of those who do not have dementia show no danger of contracting the disease. In the conclusion of the research, it was noted that most patients diagnosed with Alzheimer's are older than 65 years, indicating that this stage of life tends to trigger brain changes associated with the disease. This finding underscores the importance of considering age as a key factor in the early identification of the disease. © 2024 Elsevier B.V., All rights reserved.